We've all played that one game that never was meant to be funny but we ended up laughing when a certain character said this or someone did that. I remember playing Lord of the Rings: War of the Ring and during certain missions, your villagers that gather resources for you would be either Dwarves, Elves, or Humans (on the good side). Well, the dwarven worker epitomizes the grumpy worker. Every time you click on him or make him do something, he'd either grumble or give a one-word answer. Examples: "Waiting..." "What?" "Where?" "On it..." "Ugh...." It's just so fun to push his buttons! XD What's your experience?
I liked pushing Gladion' buttons in SM, he was so moody, even though it wasn't really pushed, he was so moody and everything I did felt like I was making him mad. Also the nurse in terraria, if you are a female iirc, she just hates you.
I suppose there's some interesting dialogue in animal crossing and stardew valley, but I don't know examples off the top of my head as I don't play the dialogue parts of them as much as I just run around doing the collecting part XD I remember that Redd gets upset if you sneeze emote near his art though